TESAMORELIN 10MG
TESAMORELIN 10MG
Tesamorelin 10mg: Clinical Overview
Tesamorelin is a synthetic peptide consisting of 44 amino acids. It is a stabilized analogue of human Growth Hormone-Releasing Factor (GRF), designed to stimulate the pituitary gland to produce and release endogenous growth hormone.
Key Characteristics
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Mechanism of Action: It binds to and activates GRF receptors in the pituitary gland. Unlike exogenous growth hormone, it preserves the body’s natural pulsatile release of GH and maintains the negative feedback loop of somatostatin.
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Primary Clinical Use: It is most notably utilized for the reduction of excess abdominal fat (visceral adipose tissue) in patients with HIV-associated lipodystrophy.
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Formulation: Typically provided as a lyophilized (freeze-dried) powder that requires reconstitution with bacteriostatic water or sterile saline.
Product Specifications
| Feature | Details |
| Molecular Formula | $C_{221}H_{366}N_{72}O_{67}S$ |
| Molecular Weight | ~5135.9 g/mol |
| Purity | Often synthesized to $\ge$ 98% purity for research/clinical applications |
| Appearance | White, sterile lyophilized cake or powder |
Potential Physiological Effects
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Lipolysis: Promotes the breakdown of lipids, specifically targeting deep visceral fat rather than subcutaneous fat.
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Metabolic Impact: May improve lipid profiles (triglycerides and cholesterol levels) as a secondary result of fat reduction.
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Cognition: Ongoing clinical research explores its potential neuroprotective effects and impact on mild cognitive impairment.
Note: For research and professional applications, ensure the vials are stored at controlled temperatures (typically 2°C to 8°C) and protected from light to maintain peptide stability.