EPITHALON 10MG

EPITHALON 10MG

LE 11,500.00
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EPITHALON 10MG
  • EPITHALON 10MG
  • EPITHALON 10MG
EPITHALON 10MG

EPITHALON 10MG

LE 11,500.00

Epithalon 10mg: Technical Description

Epithalon (also known as Epitalon or AEDG) is a synthetic tetrapeptide consisting of four amino acids: Alanine-Glutamate-Aspartate-Glycine. It was originally developed at the St. Petersburg Institute of Bioregulation and Gerontology as a synthetic version of Epithalamin, a natural peptide produced in the pineal gland.

 

Core Specifications

  • Concentration: 10mg of lyophilized (freeze-dried) powder per vial.

     

  • Molecular Formula: $C_{14}H_{22}N_{4}O_{9}$

     

  • Molecular Weight: $390.35$ g/mol

     

  • Sequence: $H-Ala-Glu-Asp-Gly-OH$

     

  • Appearance: Sterile, white/off-white lyophilized cake or powder.

     

Primary Biological Functions

  1. Telomerase Activation: Epithalon's most distinctive property is its ability to induce the production of telomerase. This enzyme repairs and lengthens telomeres (the protective caps at the ends of chromosomes), potentially slowing down cellular senescence (aging).

     

  2. Pineal Gland Support: It acts as a bioregulator for the pineal gland, helping to normalize the production of endogenous melatonin. This can help restore disrupted circadian rhythms and improve sleep quality in aging subjects.

     

  3. Antioxidant Properties: Research indicates it enhances the activity of antioxidant enzymes like superoxide dismutase (SOD) and glutathione peroxidase, which help mitigate oxidative stress.

     

  4. Immune Modulation: It has been observed to normalize T-cell function and improve the overall immune response.

     

Reconstitution & Storage

To maintain the stability of this delicate tetrapeptide, the following protocols are generally observed:

Step Guidelines
Diluent Sterile Water or Bacteriostatic Water (0.9% Benzyl Alcohol).
Mixing Add 1mL–2mL of diluent slowly down the side of the vial. Gently swirl; do not shake, as mechanical stress can denature the peptide.
Lyophilized Storage Stable at room temp for ~3 weeks; for long-term, store at $-20^\circ\text{C}$ or below.
Reconstituted Storage Must be refrigerated at $2^\circ\text{C}$ to $8^\circ\text{C}$. Use within 7–14 days for maximum potency.

Key Properties at a Glance

  • Target: Telomerase enzyme and Pineal Gland.

     

  • Purity: Typically $\ge$ 98% in high-end research grades.

  • Solubility: Highly soluble in water and saline solutions.

     

  • Primary Research Focus: Longevity, sleep cycle regulation, and age-related tissue repair.

     

Research Note: Because Epithalon is a very small peptide (only four amino acids), it is remarkably stable in its dry state compared to larger protein hormones, but it remains light-sensitive and should be stored in amber vials or dark environments.

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