PT-141 10MG

PT-141 10MG

LE 8,000.00
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PT-141 10MG
  • PT-141 10MG
  • PT-141 10MG
PT-141 10MG

PT-141 10MG

LE 8,000.00

PT-141 (Bremelanotide) 10mg: Technical Description

PT-141, scientifically known as Bremelanotide, is a synthetic cyclic heptapeptide analogue of the naturally occurring $\alpha$-Melanocyte Stimulating Hormone ($\alpha$-MSH). Originally derived from the tanning peptide Melanotan II, it was developed specifically for its potent effects on sexual arousal and libido.

 

Core Specifications

  • Concentration: 10mg of lyophilized (freeze-dried) powder per vial.

  • Molecular Formula: $C_{50}H_{68}N_{14}O_{10}$

     

  • Molecular Weight: $1025.2$ g/mol

     

  • Sequence: $Ac\text{-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH}$

     

  • Appearance: Sterile, white/off-white lyophilized powder.

     

Primary Mechanism of Action

Unlike traditional PDE5 inhibitors (like Sildenafil or Tadalafil) that act on the vascular system to increase blood flow, PT-141 operates via the Central Nervous System (CNS).

 

  1. Melanocortin Receptor Agonist: It primarily targets and activates MC3R and MC4R receptors in the hypothalamus.

     

  2. Dopamine Release: Activation of these receptors triggers a downstream release of dopamine, a key neurotransmitter involved in the biological "reward" system and sexual desire.

     

  3. Broad Efficacy: Because it acts on the brain rather than the blood vessels, it is researched for both male erectile dysfunction and Female Sexual Interest/Arousal Disorder (FSIAD).

     

Key Properties & Research Focus

  • Targeted Arousal: Highly effective for addressing psychological or hormone-related low libido.

     

  • Onset & Duration: Typically takes effect within 1.5 to 4 hours after administration. Its biological effects can last up to 24–72 hours in some subjects.

     

  • Non-Vascular: Does not rely on nitric oxide pathways, making it a subject of study for those who do not respond to traditional vascular-based treatments.

     

Reconstitution & Storage

Protocol Guidelines
Diluent Bacteriostatic Water (0.9% Benzyl Alcohol) or Sterile Saline.
Mixing Add 1mL–2mL of diluent. Swirl gently; do not shake, as the peptide chain can be sensitive to mechanical stress.
Storage (Dry) Stable at room temperature for 3-4 weeks; for long-term, store at $-20^\circ\text{C}$.
Storage (Liquid) Once reconstituted, must be kept refrigerated ($2^\circ\text{C}$ to $8^\circ\text{C}$). Use within 30 days for maximum efficacy.

Comparison at a Glance

Feature PT-141 PDE5 Inhibitors (e.g., Viagra)
Target Central Nervous System Vascular System
Primary Effect Increased Desire/Libido Increased Blood Flow
Mechanism Melanocortin Agonist PDE5 Enzyme Inhibition

Note: PT-141 is highly light-sensitive. It is recommended to store vials in a dark environment and avoid exposure to direct sunlight even during reconstitution.

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